Pendekatan Evidence Based Oral Hygiene dengan Kassa dan Spons yang Mengandung Chlorhexidin 2% dalam Pencegahan Ventilator Associated Penumonia
DOI:
https://doi.org/10.31539/bzqsn214Abstract
This study aimed to analyze the differences in effectiveness of oral hygiene measures using gauze and sponges containing 2% chlorhexidine in preventing Ventilator-Associated Pneumonia (VAP) in patients on mechanical ventilation in the ICU. A literature search was conducted through PubMed, ScienceDirect, Scopus, Google Scholar, and GARUDA databases for national and international articles published between 2017 and 2025. Seven articles that met the inclusion and exclusion criteria were systematically analyzed. The results of the literature review indicated that oral hygiene using sponges containing 2% chlorhexidine tended to be more effective than gauze in reducing oral bacterial colonization and preventing VAP. These findings suggest that selecting appropriate oral hygiene devices, along with the use of effective antiseptics, is an important component of evidence-based critical care nursing practice to reduce the risk of Ventilator-Associated Pneumonia in ICU patients.
Keywords: Chlorhexidine 2%, Gauze, Oral Hygiene, Sponge, Ventilator-Associated Pneumonia
References
Astuti, K. I., Janah, S. N., & Rosyid, F. N. (2025). Oral Hygiene Pasien ICU on Ventilator : Literature Review. Prepotif : Jurnal Kesehatan Masyarakat, 9(2), 6872–6881. https://doi.org/10.31004/prepotif.v9i2.47103
Choi, M. I., Han, S. Y., Jeon, H. S., Choi, E. S., Won, S. E., Lee, Y. J., Baek, C. Y., & Mun, S. J. (2022). The Effect of Professional Oral Care on the Oral Health Status of Critical Trauma Patients Using Ventilators. International Journal of Environmental Research and Public Health, 19(10), 6197. https://doi.org/10.3390/ijerph19106197
Fitria, N. J., Dewi, E., & Nurhayati, F. D. (2025). Implementation of Oral Hygiene with Propolis to Prevent Ventilator-Associated Pneumonia in Mechanically Ventilated ICU Patients. Indonesian Journal of Global Health Research, 7(6), 433–440. https://jurnal2.globalhealthsciencegroup.com/index.php/IJGHR/article/view/331
Garegnani, L. I., Giménez, M. L., Escobar Liquitay, C. M., & Franco, J. V. A. (2023). Oral Hygiene Interventions to Prevent Ventilator-Associated Pneumonia: A Network Meta-Analysis. Nursing in Critical Care, 28(5), 744–755. https://doi.org/10.1111/nicc.12865
Haq, M. A., Herawati, T., & Maria, R. (2023). Efektivitas Oral Care dengan Chlorhexidine dalam Mencegah Ventilator Associated Pneumonia: Systematic Review. Jurnal Keperawatan, 15(2), 833–844. https://journal2.stikeskendal.ac.id/index.php/keperawatan/article/view/1032
Indawati, E., & Rakhmawati, A. (2020). Efektivitas Kebersihan Mulut Menggunakan Larutan Klorheksidin terhadap Pencegahan Pneumonia pada Pasien dengan Penggunaan Ventilator. Jurnal Antara Keperawatan, 1(3). https://doi.org/10.37063/jurnalantarakeperawatan.v1i3.28
Iswahyudi, A. S. R., & Afik, A. (2026). Implementasi Oral Hygiene Menggunakan Antiseptik Chlorhexidine 0.2% Mencegah Ventilator Associated Pneumonia (VAP) pada Pasien Terpasang Ventilator Mekanik: Studi Kasus. Jurnal Penelitian Perawat Profesional, 8(2), 419–428. https://doi.org/10.37287/jppp.v8i2.2122
Klompas, M., Branson, R., Cawcutt, K., Crist, M., Eichenwald, E. C., Greene, L. R., Howell, M. D., Lee, G., Magill, S. S., Maragakis, L. L., Priebe, G. P., Speck, K., Yokoe, D. S., & Berenholtz, S. M. (2022). Strategies to Prevent Ventilator-Associated Pneumonia, Ventilator-Associated Events, and Nonventilator Hospital-Acquired Pneumonia in Acute-Care Hospitals: 2022 Update. Infection Control & Hospital Epidemiology, 43(6), 687–713. https://doi.org/10.1017/ice.2022.88
Köse, S., & Çoban, G. İ. (2024). Comparison of Oral Care Methods in Mechanically Ventilated ICU Patients. Nursing in Critical Care, 29(1), 45–52. https://archhealthscires.org/index.php/pub/article/view/574
Mohammad, E. B., Al Eleiwah, A. A., Qurdahji, B. T., Rayan, A., Alshraideh, J. A., Al Hadid, L. A., Al Kharabsheh, M. S., Hudhud, H. N., & Jakalat, S. (2024). Oral Care and Positioning to Prevent Ventilator-Associated Pneumonia: A Systematic Review. SAGE Open Nursing. https://doi.org/10.1177/23779608241271699
Rumtily, M. J. (2025). Pengaruh Chlorhexidine 0,2% sebagai Oral Hygiene terhadap Pencegahan Ventilator Associated Pneumon Ia (VAP) pada Pasien Gagal Nafas di Ruang ICU Rumah Sakit Immanuel Bandung. Jurnal Ilmu Kesehatan Immanuel, 19(1), 1–8. https://doi.org/10.36051/jiki.v19i1.295
Shaban, A. M., El-mokadem, N. M., & Abdallah, S. E.-S. (2021). Effectiveness of Implementing Ventilator Associated Pneumonia Prevention Bundle among Mechanically Ventilated Patients. International Journal of Novel Research in Healthcare and Nursing, 8(2), 329–342. https://www.noveltyjournals.com/upload/paper/Effectiveness%20of%20Implementing%20Ventilator.pdf
Singh, P., Arshad, Z., Srivastava, V. K., Singh, G. P., & Gangwar, R. S. (2022). Efficacy of Oral Care Protocols in the Prevention of Ventilator-Associated Pneumonia in Mechanically Ventilated Patients. Cureus. https://doi.org/10.7759/cureus.23750
Utami, Y. W., & Kristinawati, B. (2022). Oral Hygiene dalam Pencegahan Ventilator-Associated Pneumonia pada Pasien Kritis: Literature Review. Faletehan Health Journal, 9(02), 152–163. https://www.researchgate.net/profile/Beti-Kristinawati-2/publication/362232505_Oral_Hygiene_dalam_Pencegahan_Ventilator-Associated_Pneumonia_pada_Pasien_Kritis_Literature_Review/links/6581adb23c472d2e8e709ac2/Oral-Hygiene-dalam-Pencegahan-Ventilator-Associated-Pneumonia-pada-Pasien-Kritis-Literature-Review.pdf
Yamakita S, Unoki T, Niiyama S, Natsuhori E, Haruna J, Kuribara T (2024). Comparative Efficacy of Various Oral Hygiene Care Methods in Preventing Ventilator-Associated Pneumonia in Critically Ill Patients: A Systematic Review and Network Meta-Analysis. PLoS ONE 19(12): e0313057. https://doi.org/10.1371/journal.pone.0313057
Yuniandita, N., & Hudiyawati, D. (2020). Prosedur Pencegahan Terjadinya Entilator Associated Neumonia (VAP) di Ruang Intensive Care Unit (ICU): A Literature Review. Jurnal Berita Ilmu Keperawatan, 13(1), 62–74. https://journals.ums.ac.id/BIK/article/view/11604
Yunus, P., Damansyah, H., & Talib, A. S. (2025). Pengaruh Oral Hygiene terhadap Pencegahan Ventilator Associated Pneumonia (VAP) di Ruang ICU. Prepotif : Jurnal Kesehatan Masyarakat, 9(1), 2630–2638. https://doi.org/10.31004/prepotif.v9i1.41374
Zambrano, T. B. S., Guillén Vivas, X. S., Santos, C. B., Mestre, V. F., Maddela, N. R., Galarza Santana, L. E., & Couto de Almeida, R. S. (2024). Evaluation of Brushing Efficiency in Reducing Rral Microbiota in Mechanically Ventilated Patients Admitted to an Intensive Care Unit. Infection Prevention in Practice, 6(1), 100346. https://doi.org/10.1016/j.infpip.2024.100346
Zand, F., Zahed, L., Mansouri, P., Dehghanrad, F., Bahrani, M., & Ghorbani, M. (2017). The Effects of Oral Rinse with 0.2% and 2% Chlorhexidine on Oropharyngeal Colonization and Ventilator-associated Pneumonia in Adults’ Intensive Care Units. Journal of Critical Care, 40, 318–322. https://doi.org/10.1016/j.jcrc.2017.02.029
Zhao, T., Wu, X., Zhang, Q., Li, C., Worthington, H. V, & Hua, F. (2020). Oral Hygiene Care for Critically Ill Patients to Prevent Ventilator-Associated Pneumonia. Cochrane Database of Systematic Reviews, 2020(12). https://pubmed.ncbi.nlm.nih.gov/33368159/
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Nazhifa Nida Iftina, Erina Adriana Paramitha, Amaliah Mahmudah, Sri Rahayu, Endar Sulistyo

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

