Peningkatan Imunitas Ibu Nifas Melalui Senyawa Flavonoid Hasil Ekstraksi Lemon (Citrus Limon) Menggunakan Teknologi Ultrasound Assisted Extraction
Abstract
This study aims to determine the effectiveness of the extraction of lemon liquid (citrus limon) using Ultrasound Assisted Extraction (UAE) technology against increasing the immunity of puerperal mothers. The method used is true experiment with randomized pretest and posttest with control group design. The results showed that the average increase in immunity of postpartum mothers in the pretest intervention group was 264.66 and posttest was 328.16 while in the control group the average result of increasing immunity was 208.76 and posttest was 137.05. The conclusion of giving the results of the extraction of lemon liquid (citrus limon) using Ultrasound Assisted Extraction (UAE) technology at a dose of 7grams / 175ml given for 14 days was proven to have an effect on increasing the immunity of postpartum mothers with a p value of <0.05.
Keywords : Immunity, Mother Puerperium, Flavonoid Compounds, Lemon Extraction, Ultrasound Assisted Extraction (UAE).
References
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Ridhwan Anshor Alfauzi, Lilis Hartati, Danes Suhendra, Tri Puji Rahayu, & Hidayah, N. (2022). Ekstraksi Senyawa Bioaktif Kulit Jengkol (Archidendron jiringa) dengan Konsentrasi Pelarut Metanol Berbeda sebagai Pakan Tambahan Ternak Ruminansia. Jurnal Ilmu Nutrisi Dan Teknologi Pakan, 20(3), 95–103. https://doi.org/10.29244/jintp.20.3.95-103
Saini, R. K., Ranjit, A., Sharma, K., Prasad, P., Shang, X., Gowda, K. G. M., & Keum, Y.-S. (2022). Bioactive Compounds of Citrus Fruits: A Review of Composition and Health Benefits of Carotenoids, Flavonoids, Limonoids, and Terpenes. Antioxidants, 11(2), 239. https://doi.org/10.3390/antiox11020239
Sirait, L. I. (2021). Air Susu Ibu (ASI) sebagai Pertahanan Tubuh (Imunitas) Bayi. Manajemen Laktasi Berbasis Evidence Based Terkini. https://doi.org/10.46984/978-623-94453-9-3-1456
Špiljak, B., Vilibić, M., Glavina, A., Crnković, M., Šešerko, A., & Lugović-Mihić, L. (2022). A Review of Psychological Stress among Students and Its Assessment Using Salivary Biomarkers. Behavioral Sciences, 12(10), 400. https://doi.org/10.3390/bs12100400
Sugiyono. (2019). Metode Penelitian Kuantitatif, Kualitatif, Dan R&D (I). (Sutopo, ed) Alfabeta.
Yuniarto, K., Okta Muvianto, C. M., & Ernia, E. (2021). Aplikasi Ultrasound Assisted Extraction untuk Produksi Minyak Bawang Putih Varietas Lokal. Jurnal Teknologi Pertanian, 22(3), 177–186. https://doi.org/10.21776/ub.jtp.2021.022.03.3
Zhuo, L. C., Abang Zamhari, D. N. J. binti, Yong, A. S. K., Shapawi, R., & Lin, Y. H. (2021). Effects of Fermented Lemon Peel Supplementation in Diet on Growth, Immune Responses, and Intestinal Morphology of Asian Sea Bass, Lates Calcarifer. Aquaculture Reports, 21. https://doi.org/10.1016/j.aqrep.2021.100801
Bayat, P., Farshchi, M., Yousefian, M., Mahmoudi, M., & Yazdian-Robati, R. (2021). Flavonoids, the Compounds with Anti-Inflammatory and Immunomodulatory Properties, As Promising Tools in Multiple Sclerosis (MS) Therapy: A Systematic Review of Preclinical Evidence. In International Immunopharmacology (Vol. 95). Elsevier B.V. https://doi.org/10.1016/j.intimp.2021.107562
Chandra, B., Asra, R., & Mevia, N. A. (2022). Perbedaan Ekstraksi Daun Teratai (Nymphaea Pubescens Willd) sebagai Fungsi Aktivitas Antioksidan. Jurnal Farmasi Higea, 14(1), 28. https://doi.org/10.52689/higea.v14i1.434
Habib, H., Prabowo, Y., Sulistio, S., Mulyana, R. M., & Albar, I. A. (2023). The Association of the COVID-19 Outbreak with in-Hospital Mortality: A Single-Centre Study from Indonesia. Clinical Epidemiology and Global Health, 20, 101219. https://doi.org/10.1016/j.cegh.2023.101219
Haida, Z., Ab Ghani, S., Juju Nakasha, J., & Hakiman, M. (2022). Determination of Experimental Domain Factors of Polyphenols, Phenolic Acids snd Flavonoids of Lemon (Citrus Limon) Peel Using Two-Level Factorial Design. Saudi Journal of Biological Sciences, 29(1), 574–582. https://doi.org/10.1016/j.sjbs.2021.09.022
Hastuti, Y. D., & Kunti Mulangsri, D. A. (2022). Perbedaan Kadar Flavonoid Total Ekstrak Daun Salam (Syzygium Polyanthum) dengan Metode Refluks dari Beberapa Jenis Pelarut dan Aktivitas Antibakteri. Jurnal Ilmu Farmasi Dan Farmasi Klinik, 18(2), 85. https://doi.org/10.31942/jiffk.v18i2.5962
Jihan Hana Fauziah, Kiki Mulkiya Yuliawati, & Vinda Maharani Patricia. (2022). Pengaruh Perbedaan Pelarut Ekstraksi terhadap Aktivitas Antioksidan Ekstrak Kulit Buah Naga yang Diekstraksi dengan Metode Ultrasound-Assisted Extraction (UAE). Bandung Conference Series: Pharmacy, 2(2). https://doi.org/10.29313/bcsp.v2i2.3584
Karlsson, O., Kim, R., Hasman, A., & Subramanian, S. v. (2021). Consumption of Vitamin-A-Rich Foods and Vitamin A Supplementation for Children under Two Years Old in 51 Low- and Middle-Income Countries. Nutrients, 14(1), 188. https://doi.org/10.3390/nu14010188
Kurnianingsih, N., Ratnawati, R., Fatchiyah, F., Barlianto, W., Ali, M. M., Safitri, A., & Suyanto, E. (2019). The Difference of Amino Acid Profiling from Two Morphological Purple Sweet Potatoes From Kawi Mountain Cultivars, East Java, Indonesia. Journal of Physics: Conference Series, 1374(1), 012017. https://doi.org/10.1088/1742-6596/1374/1/012017
Kurnianingsih, Suharjono, A., Suryono, Widyowati, R., & Kubota, N. (2021). Optimization of Moringa Leaf Extraction and Time Series-based Forecasting for an Early Warning System during Extraction. 2021 IEEE Region 10 Symposium (TENSYMP), 1–6. https://doi.org/10.1109/TENSYMP52854.2021.9550816
Mehta, N., S, Jeyapriya., Kumar, P., Verma, A. K., Umaraw, P., Khatkar, S. K., Khatkar, A. B., Pathak, D., Kaka, U., & Sazili, A. Q. (2022). Ultrasound-Assisted Extraction and the Encapsulation of Bioactive Components for Food Applications. Foods, 11(19), 2973. https://doi.org/10.3390/foods11192973
Naudé, P. J. W., Pariante, C., Hoffman, N., Koopowitz, S. M., Donald, K. A., Zar, H. J., & Stein, D. J. (2022). Antenatal Maternal Depression, Early Life Inflammation and Neurodevelopment in a South African birth cohort. Brain, Behavior, and Immunity, 105, 160–168. https://doi.org/10.1016/j.bbi.2022.07.001
Nursuprianah, I., Heryandi, Y., & Risdianto, R. (2022). Manfaat Jamu Empon-Empon untuk Peningkatan Imunitas Tubuh pada Masa Pandemi Covid-19. Dimasejati: Jurnal Pengabdian Kepada Masyarakat, 4(1), 105. https://doi.org/10.24235/dimasejati.v4i1.10846
Ridhwan Anshor Alfauzi, Lilis Hartati, Danes Suhendra, Tri Puji Rahayu, & Hidayah, N. (2022). Ekstraksi Senyawa Bioaktif Kulit Jengkol (Archidendron jiringa) dengan Konsentrasi Pelarut Metanol Berbeda sebagai Pakan Tambahan Ternak Ruminansia. Jurnal Ilmu Nutrisi Dan Teknologi Pakan, 20(3), 95–103. https://doi.org/10.29244/jintp.20.3.95-103
Saini, R. K., Ranjit, A., Sharma, K., Prasad, P., Shang, X., Gowda, K. G. M., & Keum, Y.-S. (2022). Bioactive Compounds of Citrus Fruits: A Review of Composition and Health Benefits of Carotenoids, Flavonoids, Limonoids, and Terpenes. Antioxidants, 11(2), 239. https://doi.org/10.3390/antiox11020239
Sirait, L. I. (2021). Air Susu Ibu (ASI) sebagai Pertahanan Tubuh (Imunitas) Bayi. Manajemen Laktasi Berbasis Evidence Based Terkini. https://doi.org/10.46984/978-623-94453-9-3-1456
Špiljak, B., Vilibić, M., Glavina, A., Crnković, M., Šešerko, A., & Lugović-Mihić, L. (2022). A Review of Psychological Stress among Students and Its Assessment Using Salivary Biomarkers. Behavioral Sciences, 12(10), 400. https://doi.org/10.3390/bs12100400
Sugiyono. (2019). Metode Penelitian Kuantitatif, Kualitatif, Dan R&D (I). (Sutopo, ed) Alfabeta.
Yuniarto, K., Okta Muvianto, C. M., & Ernia, E. (2021). Aplikasi Ultrasound Assisted Extraction untuk Produksi Minyak Bawang Putih Varietas Lokal. Jurnal Teknologi Pertanian, 22(3), 177–186. https://doi.org/10.21776/ub.jtp.2021.022.03.3
Zhuo, L. C., Abang Zamhari, D. N. J. binti, Yong, A. S. K., Shapawi, R., & Lin, Y. H. (2021). Effects of Fermented Lemon Peel Supplementation in Diet on Growth, Immune Responses, and Intestinal Morphology of Asian Sea Bass, Lates Calcarifer. Aquaculture Reports, 21. https://doi.org/10.1016/j.aqrep.2021.100801
Published
2024-02-05
Section
Articles
Copyright (c) 2024 Camilla Septiani, Melyana Nurul Widyawati, Kurnianingsih Kurnianingsih, Sudiyono Sudiyono, Edy Susanto
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