Penggunaan Negative Pressure Wound Therapy (NPWT) terhadap Diabetic Foot Ulcer
Abstract
This study aims to conduct a literature review related to research results that discusses the effectiveness of NPWT on diabetic foot ulcers (DFU). The method used is a systematic review method from online databases such as Scopus, ClinicalKey, ClinicalKey Nursing, EBSCOhost, Proquest, ScienceDirect, Springer Link, Pubmed, and SAGE Journals using the keywords diabetes mellitus, negative pressure wound therapy, NPWT, and diabetic foot ulcer. The search uses the boolean logic "AND" and "OR". The results of a systematic review study obtained six articles describing showing that NPWT can help speed up the healing process of DFU wounds. In conclusion, the use of Negative Pressure Wound Therapy (NPWT) in wound care is a relatively effective treatment method for diabetic foot wounds.
Keywords: Diabetes Mellitus, Diabetic Foot Wounds, NPWT, Negative Pressure Wound Therapy
References
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De Souza, S. C., Mendes, C. M. C., Meneses, J. V. L., & Dias, R. M. (2022). Simplified Vacuum Dressing System: Effectiveness and Safety in Wounds Management. Acta Cirurgica Brasileira, 37(9). https://doi.org/10.1590/acb370906
Dincer, B., & Bahçecik, N. (2021). The Effect of A Mobile Application on the Foot Care of Individuals with Type 2 Diabetes: A Randomised Controlled Study. Health Education Journal, 80(4), 425–437. https://doi.org/10.1177/0017896920981617
Faraji, N., Goli, R., Choobianzali, B., Bahrami, S., Sadeghian, A., Sepehrnia, N., & Ghalandari, M. (2021). Ozone Therapy As An Alternative Method for the Treatment of Diabetic Foot Ulcer: A Case Report. Journal of Medical Case Reports, 15(1), 1–9. https://doi.org/10.1186/s13256-021-02829-y
Jia, Z., Liu, L., Zhang, S., Zhao, X., Luo, L., Tang, Y., Shen, B., & Chen, M. (2021). Proteomics Changes after Negative Pressure Wound Therapy in Diabetic Foot Ulcers. Molecular Medicine Reports, 24(6), 1–16. https://doi.org/10.3892/mmr.2021.12474
Kalsum, U., Anwar H, S., Astrid, A., & Jumari, J. (2020). Penerapan Program Edukasi Perawatan Kaki (3STEPFUN) dalam Meningkatkan Perilaku Merawat Kaki untuk Pencegahan Ulkus Diabetikum pada Pasien Diabetes Mellitus Tipe 2 di Aliansi Rumah Sakit Islam Jakarta Tahun 2019. Jurnal Bidang Ilmu Kesehatan, 10(2), 151–159. https://doi.org/10.52643/jbik.v10i2.1067
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Maranna, H., Lal, P., Mishra, A., Bains, L., Sawant, G., Bhatia, R., Kumar, P., & Beg, M. Y. (2021). Negative Pressure Wound Therapy in Grade 1 and 2 Diabetic Foot Ulcers: A Randomized Controlled Study. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 15(1), 365–371. https://doi.org/10.1016/j.dsx.2021.01.014
Mohamed, S., Wahed, A., Taha, N. M., Ali, H. H., & Mahmoud, S. (2021). Nursing Guidelines for Diabetic Foot Ulcer Care: An Intervention Study. Annals of R.S.C.B, 25(3), 5128–5139. https://www.annalsofrscb.ro/index.php/journal/article/view/2016
Przybek-Mita, J., Bazaliński, D., Szewczyk, M. T., Kardyś, D., Mańkowski, B., & Więch, P. (2023). Nurses’ Readiness to Undertake Controlled Negative Pressure Therapy in the Treatment of Chronic Wounds-Research Report. International Journal of Environmental Research and Public Health, 20(4). https://doi.org/10.3390/ijerph20043388
Schaper, N. C., van Netten, J. J., Apelqvist, J., Bus, S. A., Hinchliffe, R. J., & Lipsky, B. A. (2020). Practical Guidelines on the Prevention and Management of Diabetic Foot Disease (IWGDF 2019 Update). Diabetes/Metabolism Research and Reviews, 36(S1), 1–10. https://doi.org/10.1002/dmrr.3266
Seidel, D., Lefering, R., Storck, M., Lawall, H., Wozniak, G., Mauckner, P., Hochlenert, D., Wetzel-Roth, W., Sondern, K., Hahn, M., Rothenaicher, G., Krönert, T., & Zink, K. (2022). NPWT Resource Use Compared with Standard Moist Wound Care in Diabetic Foot Wounds: DiaFu Randomized Clinical Trial Results. Journal of Foot and Ankle Research, 15(1), 1–15. https://doi.org/10.1186/s13047-022-00569-w
Stiehl, J. B. (2020). Failure of Healing in Chronic Diabetic Wounds: A Case Report. Advances in Skin & Wound Care, 33(11), 1–5. https://doi.org/10.1097/01.ASW.0000717896.88988.43
Tekale, S., Varma, A., Tekale, S., & Kumbhare, U. (2022). A Review on Newer Interventions for the Prevention of Diabetic Foot Disease. Cureus, 14(10), 1–9. https://doi.org/10.7759/cureus.30591
Wu, M., Matar, D. Y., Yu, Z., Chen, Z., Knoedler, S., Ng, B., Darwish, O. A., Sohrabi, S., Friedman, L., Haug, V., Murphy, G. F., Rinkevich, Y., Orgill, D. P., & Panayi, A. C. (2022). Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing. Pharmaceutics, 14(10). https://doi.org/10.3390/pharmaceutics14102125
Wu, Y., Chen, L., Wu, S., Yu, L., Chen, M., Wang, J., Chen, J., & Pang, Q. (2021). Application Of A Simple Skin Stretching System and Negative Pressure Wound therapy in Repair of Complex Diabetic Foot Wounds. Journal of Orthopaedic Surgery and Research, 16(1), 1–9. https://doi.org/10.1186/s13018-021-02405-6
Aldana, P. C., & Khachemoune, A. (2020). Diabetic Foot Ulcers: Appraising Standard of Care and Reviewing New Trends in Management. American Journal of Clinical Dermatology, 21(2), 255–264. https://doi.org/10.1007/S40257-019-00495-X
Alkhatieb, M., Mortada, H., & Aljaaly, H. (2020). Management of a Difficult-to-Treat Diabetic Foot Wound Complicated by Osteomyelitis: A Case Study. Case Reports in Surgery, 2020, 1–7. https://doi.org/10.1155/2020/3971581
Boyko, E. J., Karuranga, D. J. M. S., Piemonte, L., & Saeedi, H. S. P. R. P. (2021). International Diabetes Federation. Diabetes Research and Clinical Practice, 102(2). https://doi.org/10.1016/j.diabres.2013.10.013
De Oliveira Leite, T. F., da Silva, E. R., & Joviliano, E. E. (2021). Effect of Negative Pressure Wound Therapy for Legs in Complex Wound Diabetic Patients: Therapeutic Challenge and Review. SAGE Open Medical Case Reports, 9. https://doi.org/10.1177/2050313X211025920
De Souza, S. C., Mendes, C. M. C., Meneses, J. V. L., & Dias, R. M. (2022). Simplified Vacuum Dressing System: Effectiveness and Safety in Wounds Management. Acta Cirurgica Brasileira, 37(9). https://doi.org/10.1590/acb370906
Dincer, B., & Bahçecik, N. (2021). The Effect of A Mobile Application on the Foot Care of Individuals with Type 2 Diabetes: A Randomised Controlled Study. Health Education Journal, 80(4), 425–437. https://doi.org/10.1177/0017896920981617
Faraji, N., Goli, R., Choobianzali, B., Bahrami, S., Sadeghian, A., Sepehrnia, N., & Ghalandari, M. (2021). Ozone Therapy As An Alternative Method for the Treatment of Diabetic Foot Ulcer: A Case Report. Journal of Medical Case Reports, 15(1), 1–9. https://doi.org/10.1186/s13256-021-02829-y
Jia, Z., Liu, L., Zhang, S., Zhao, X., Luo, L., Tang, Y., Shen, B., & Chen, M. (2021). Proteomics Changes after Negative Pressure Wound Therapy in Diabetic Foot Ulcers. Molecular Medicine Reports, 24(6), 1–16. https://doi.org/10.3892/mmr.2021.12474
Kalsum, U., Anwar H, S., Astrid, A., & Jumari, J. (2020). Penerapan Program Edukasi Perawatan Kaki (3STEPFUN) dalam Meningkatkan Perilaku Merawat Kaki untuk Pencegahan Ulkus Diabetikum pada Pasien Diabetes Mellitus Tipe 2 di Aliansi Rumah Sakit Islam Jakarta Tahun 2019. Jurnal Bidang Ilmu Kesehatan, 10(2), 151–159. https://doi.org/10.52643/jbik.v10i2.1067
Lavery, L. A., Davis, K. E., La Fontaine, J., Farrar, J. D., Bhavan, K., Oz, O. K., & Crisologo, P. A. (2020). Does Negative Pressure Wound Therapy with Irrigation Improve Clinical Outcomes? A Randomized Clinical Trial in Patients with Diabetic Foot Infections. American Journal of Surgery, 220(4), 1076–1082. https://doi.org/10.1016/j.amjsurg.2020.02.044
Maranna, H., Lal, P., Mishra, A., Bains, L., Sawant, G., Bhatia, R., Kumar, P., & Beg, M. Y. (2021). Negative Pressure Wound Therapy in Grade 1 and 2 Diabetic Foot Ulcers: A Randomized Controlled Study. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 15(1), 365–371. https://doi.org/10.1016/j.dsx.2021.01.014
Mohamed, S., Wahed, A., Taha, N. M., Ali, H. H., & Mahmoud, S. (2021). Nursing Guidelines for Diabetic Foot Ulcer Care: An Intervention Study. Annals of R.S.C.B, 25(3), 5128–5139. https://www.annalsofrscb.ro/index.php/journal/article/view/2016
Przybek-Mita, J., Bazaliński, D., Szewczyk, M. T., Kardyś, D., Mańkowski, B., & Więch, P. (2023). Nurses’ Readiness to Undertake Controlled Negative Pressure Therapy in the Treatment of Chronic Wounds-Research Report. International Journal of Environmental Research and Public Health, 20(4). https://doi.org/10.3390/ijerph20043388
Schaper, N. C., van Netten, J. J., Apelqvist, J., Bus, S. A., Hinchliffe, R. J., & Lipsky, B. A. (2020). Practical Guidelines on the Prevention and Management of Diabetic Foot Disease (IWGDF 2019 Update). Diabetes/Metabolism Research and Reviews, 36(S1), 1–10. https://doi.org/10.1002/dmrr.3266
Seidel, D., Lefering, R., Storck, M., Lawall, H., Wozniak, G., Mauckner, P., Hochlenert, D., Wetzel-Roth, W., Sondern, K., Hahn, M., Rothenaicher, G., Krönert, T., & Zink, K. (2022). NPWT Resource Use Compared with Standard Moist Wound Care in Diabetic Foot Wounds: DiaFu Randomized Clinical Trial Results. Journal of Foot and Ankle Research, 15(1), 1–15. https://doi.org/10.1186/s13047-022-00569-w
Stiehl, J. B. (2020). Failure of Healing in Chronic Diabetic Wounds: A Case Report. Advances in Skin & Wound Care, 33(11), 1–5. https://doi.org/10.1097/01.ASW.0000717896.88988.43
Tekale, S., Varma, A., Tekale, S., & Kumbhare, U. (2022). A Review on Newer Interventions for the Prevention of Diabetic Foot Disease. Cureus, 14(10), 1–9. https://doi.org/10.7759/cureus.30591
Wu, M., Matar, D. Y., Yu, Z., Chen, Z., Knoedler, S., Ng, B., Darwish, O. A., Sohrabi, S., Friedman, L., Haug, V., Murphy, G. F., Rinkevich, Y., Orgill, D. P., & Panayi, A. C. (2022). Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing. Pharmaceutics, 14(10). https://doi.org/10.3390/pharmaceutics14102125
Wu, Y., Chen, L., Wu, S., Yu, L., Chen, M., Wang, J., Chen, J., & Pang, Q. (2021). Application Of A Simple Skin Stretching System and Negative Pressure Wound therapy in Repair of Complex Diabetic Foot Wounds. Journal of Orthopaedic Surgery and Research, 16(1), 1–9. https://doi.org/10.1186/s13018-021-02405-6
