Strategi Intervensi untuk Mengeliminasi Kasus Tuberkulosis

  • Anggreni Ade Putri Universitas Airlangga
  • Sri Widati Universitas Airlangga
  • Mochammad Bagus Qomaruddin Universitas Airlangga
  • Yulia Yunara Universitas Lambung Mangkurat


This study aims to analyze tuberculosis intervention strategies in Southeast Asia. The method used is a systematic review. The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) as a guide and The Joanna Briggs Institute (JBI) were used to conduct quality assessment. Data were born in the Scopus, Science Direct, and Pubmed databases on articles published in the last five years. In the final review, ten papers were included. The research results show that the intervention strategy is divided into three categories: community-based support through health cadres, nutritional status support, and investigation of household contacts and early detection. In conclusion, efforts to eliminate TB cases require a full-scale strategy with evidence-based interventions in identifying risk factors, contact investigation, and successful treatment.


Keywords: Southeast Asia, TB Elimination, İntervention, Strategy, Tuberculosis


Barliana, M. I., Kusuma, A. S. W., Insani, W. N., Alfian, S. D., Diantini, A., Mutakin, M., Rostinawati, T., Herlambang, H., Puspitasari, I. M., Suwantika, A. A., & Abdulah, R. (2021). Genetic Variation of ABCB1 and CYP2E1 with the Duration of Tuberculosis Therapy: A Pilot Study among Tuberculosis Patients in Indonesia. BMC Research Notes, 14(1), 295.

Carroll, A., Vincenti-Delmas, M., Maung, B. M., Htun, W. P. P., Nosten, F., Smith, C., & Sonnenberg, P. (2020). TB Outcomes and Mortality Risk Factors in Adult Migrants at the Thailand-Myanmar Border. The International Journal of Tuberculosis and Lung Disease : The Official Journal of the International Union against Tuberculosis and Lung Disease, 24(10), 1009–1015.

Charoensakulchai, S., Lertpheantum, C., Aksornpusitpong, C., Trakulsuk, P., Sakboonyarat, B., Rangsin, R., Mungthin, M., & Piyaraj, P. (2021). Six-Year Trend and Risk Factors of Unsuccessful Pulmonary Tuberculosis Treatment Outcomes in Thai Community Hospital. BMC Research Notes, 14(1), 89.

Clark, R. A., Mukandavire, C., Portnoy, A., Weerasuriya, C. K., Deol, A., Scarponi, D., Iskauskas, A., Bakker, R., Quaife, M., Malhotra, S., Gebreselassie, N., Zignol, M., Hutubessy, R. C. W., Giersing, B., Jit, M., Harris, R. C., Menzies, N. A., & White, R. G. (2023). The İmpact of Alternative Delivery Strategies for Novel Tuberculosis Vaccines in Low-İncome and Middle-İncome Countries: A Modelling Study. The Lancet Global Health, 11(4), e546–e555.

Darnton-Hill, I., Mandal, P. P., de Silva, A., Bhatia, V., & Sharma, M. (2022). Opportunities to Prevent and Manage Undernutrition to Amplify Efforts to End TB. The International Journal of Tuberculosis and Lung Disease : The Official Journal of the International Union against Tuberculosis and Lung Disease, 26(1), 6–11.

Das, A., Saimala, G., Reddy, N., Mishra, P., Giri, R., Kumar, A., Raj, A., Kumar, G., Chaturvedi, S., Babu, S., Srikantiah, S., & Mahapatra, T. (2020). Mid-Upper Arm Circumference as a Substitute of The Body Mass İndex for Assessment of Nutritional Status among Adult and Adolescent Females: Learning From an İmpoverished Indian State. Public Health, 179, 68–75.

Edwards, T., White, L. V, Lee, N., Castro, M. C., Saludar, N. R., Faguer, B. N., Fuente, N. D., Mayoga, F., Ariyoshi, K., Garfin, A. M. C. G., Solon, J. A., & Cox, S. E. (2020). Effects of Comorbidities on Quality of Life in Filipino People with Tuberculosis. The International Journal of Tuberculosis and Lung Disease : The Official Journal of the International Union against Tuberculosis and Lung Disease, 24(7), 712–719.

Kim, S., de los Reyes V, A. A., & Jung, E. (2020). Country-Specific İntervention Strategies for Top Three TB Burden Countries Using Mathematical Model. PLOS ONE, 15(4), 1–18.

Lopes, C., Kundu, D., Da Costa Barreto, I., da Cruz, B., Siva Kumar, S., Ramalingam, S., Dean, A. S., Bhatia, V., Seenivasan, P., Padmapriyadarsini, C., & Auguet, O. T. (2022). Experience on The First National Anti-TB Drug Resistance Survey (DRS) in Timor-Leste. Global Health Research and Policy, 7(1), 16.

Mallari, E., Lasco, G., Sayman, D. J., Amit, A. M. L., Balabanova, D., & Mckee, M. (2020). Connecting communities To Primary Care : A Qualitative Study on The Roles, Motivations and Lived Experiences of Community Health Workers in The Philippines. BMC Health Serv Res 20, 860 (2020).

Querri, A. G., Ohkado, A., Kawatsu, L., Bernejo, J., Vianzon, A., Recidoro, M. J., & Medina, A. (2020). Assessment of The Role of Community Health Volunteers in Delivering Primary Health Care in Manila , the Philippines. Journal of International Health, 35(1), 15–25.

Setianingrum, F., Rozaliyani, A., Adawiyah, R., Syam, R., Tugiran, M., Sari, C. Y. I., Nandipinto, F., Ramnath, J., Arifin, A. R., Handayani, D., Burhan, E., Rumende, M., Wahyuningsih, R., Rautemaa-Richardson, R., & Denning, D. W. (2022). A Prospective Longitudinal Study of Chronic Pulmonary Aspergillosis in Pulmonary Tuberculosis in Indonesia (APICAL). Thorax, 77(8), 821–828.

Sharani, Z. Z., Ismail, N., Yasin, S. M., Zakaria, Y., Razali, A., Demong, N. A. R., Mohammad, M., & Ismail, Z. (2022). Characteristics and Determinants of Loss to Follow-Up Among Tuberculosis (TB) Patients Who Smoke in an İndustrial State of Malaysia: A Registry-Based Study of the Years 2013-2017. BMC Public Health, 22(1), 638.

Shariff, N. M., Shah, S. A., & Kamaludin, F. (2019). Impact of Ethnic Disparities on the Treatment Outcomes of HIV-Negative Drug-Resistant Tuberculosis Patients in Kuala Lumpur, Malaysia: A Call for a Culturally-Sensitive Community İntervention Approach. Journal of Global Antimicrobial Resistance, 19, 274–279.

Silitonga, P., Jiang, W., Wyatt, S., Burhan, E., Kes, E. F. M., & Long, Q. (2023). Factors Affecting Time to Treatment İnitiation after Diagnosis for Multidrug-Resistant/Rifampicin-Resistant Tuberculosis Patients: A Mixed-Methods Study in Jakarta, Indonesia. Tropical Medicine & International Health : TM & IH, 28(1), 43–52.

Siongco, K. L. L., Nakamura, K., Seino, K., Moncatar, T. J. R. T., Tejero, L. M. S., De La Vega, S. A. F., Bonito, S. R., Javier, R., Tsutsui, T., Tashiro, Y., Al-Sobaihi, S., Lorenzo, F. M. E., & Canila, C. C. (2021). Improving Community Health Workers' Attitudes toward Collaborative Practice in the Care of Older Adults: An In-Service Training Intervention Trial in the Philippines. International Journal of Environmental Research and Public Health, 18(19), 9986.

Suliman, Q., Lim, P. Y., Said, S., Tan, K. A., & Zulkefli, N. A. M. (2022). Risk Factors for Early TB Treatment İnterruption among Newly Diagnosed Patients in Malaysia. Scientific Reports, 12(1), 745.

Velen, K., Nhung, N. V., Anh, N. T., Cuong, P. D., Hoa, N. B., Cuong, N. K., Dung, N. H., Sy, D. N., Britton, W. J., Marks, G. B., & Fox, G. J. (2021). Risk Factors for Tuberculosis (TB) Among Household Contacts of Patients With Smear-Positive TB in 8 Provinces of Vietnam: A Nested Case-Control Study. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 73(9), e3358–e3364.

Vo, L. N. Q., Nguyen, V. N., Nguyen, N. T. T., Dong, T. T. T., Codlin, A., Forse, R., Truong, H. T., Nguyen, H. B., Dang, H. T. M., Truong, V. Van, Nguyen, L. H., Mac, T. H., Le, P. T., Tran, K. T., Ndunda, N., Caws, M., & Creswell, J. (2023). Optimising Diagnosis and Treatment of Tuberculosis İnfection in Community and Primary Care Settings in Two Urban Provinces of Viet Nam: A Cohort Study. BMJ Open, 13(2), e071537.

World Health Organization. (2022a). Global Tuberculosis Report WHO 2022 (World Health Organization (ed.)). World Health Organization.

World Health Organization. (2022b). Tuberculosis.

World Health Organization. (2023). Tuberculosis in SEA Region.

Wrohan, I., Nguyen, T. A., Nguyen, V. N., Nguyen, B. H., Hoang, T. T. T., Nguyen, P. C., Velen, K., Marks, G. B., & Fox, G. J. (2022). Predictors of Treatment Outcomes Among Patients with Multidrug-Resistant Tuberculosis in Vietnam: A Retrospective Cohort Study. BMC Infectious Diseases, 22(1), 68.

Yerramsetti, S., Cohen, T., Atun, R., & Menzies, N. A. (2022). Global Estimates of Paediatric Tuberculosis İncidence in 2013–19: A Mathematical Modelling Analysis. The Lancet Global Health, 10(2), e207–e215.
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