Potensi Susu Fermentasi dalam Mempengaruhi Parameter
Keywords:
Anemia, Probiotik, Penyerapan Fe, Susu Fermentasi, Status Zat Besi
Abstract
This study aims to explain the effect of milk on hematological parameters. The method used is a literature review made through a systematic approach, using the PICO method, by searching for articles in the Pubmed, Scopus, and EBSCOhost databases. The research results showed that 425 articles were found, and seven articles met the inclusion criteria; these articles were fermented milk containing lactic acid bacteria, which are probiotics. Fermented milk products such as yogurt, Yakult, kefir, active, fermented goat's milk, and dahi influence hematological parameters. Namely, they can increase hemoglobin, ferritin, and erythrocyte count and reduce MCV. Milk fermentation affects hematological parameters, namely increasing hemoglobin, ferritin, and erythrocyte count and reducing MCV.
Keywords: Anemia, Probiotics, Fe Absorption, Fermented Milk, Iron Status
References
Ahmad, A. M. R., Ahmed, W., Iqbal, S., Javed, M., Rashid, S., & Iahtisham-ul-Haq. (2021). Prebiotics and Iron Bioavailability? Unveiling the Hidden Association - A Review. Trends in Food Science and Technology, 110, 584–590. https://doi.org/10.1016/j.tifs.2021.01.085
Barkhidarian, B., Roldos, L., Iskandar, M. M., Saedisomeolia, A., & Kubow, S. (2021). Probiotic Supplementation and Micronutrient Status in Healthy Subjects: A Systematic Review of Clinical Trials. Nutrients, 13(9), 1–20. https://doi.org/10.3390/nu13093001
Bintsis, T., & Papademas, P. (2022). The Evolution of Fermented Milks, from Artisanal to Industrial Products: A Critical Review. Fermentation, 8(12), 1–21. https://doi.org/10.3390/fermentation8120679
Gohel, M. K., Prajapati, J. B., Mudgal, S. V., Pandya, H. V., Singh, U. S., Trivedi, S. S., Phatak, A. G., & Patel, R. M. (2016). Effect of Probiotic Dietary Intervention on Calcium and Haematological Parameters in Geriatrics. Journal of Clinical and Diagnostic Research, 10(4), LC05–LC09. https://doi.org/10.7860/JCDR/2021/18877.7627
Gomaa, M. A. E., Allam, M. G., Haridi, A. A. I. M., Eliwa, A. E. M., & Darwish, A. M. G. (2022). High-Protein Concentrated Pro-Yogurt (Pro-WPI) Enriched with Whey Protein Isolate Improved Athletic Anemia and Performance in a Placebo-Controlled Study. Frontiers in Nutrition, 8, 1–10. https://doi.org/10.3389/fnut.2021.788446
Helmizar, H., & Surono, I. S. (2020). Characteristics of Amino Acid, Micronutrient and Probiotic Isolated from Dadih and Their Benefits for Pregnant Mothers and Outcomes in West Sumatra, Indonesia. Global Journal of Health Science, 12(1), 116-123. https://doi.org/10.5539/gjhs.v12n1p116
Helmyati, S., Rahayu, E. S., Kandarina, B. J. I ., & Juffrie, M. (2020). No Difference between Iron Supplementation Only and Iron Supplementation with Synbiotic Fermented Milk on Iron Status, Growth, and Gut Microbiota Profile in Elementary School Children with Iron Deficiency. Current Nutrition & Food Science, 16(2), 1–8. https://doi.org/10.2174/1573401314666181017110706
Hemphill, N. O., Pezley, L., Steffen, A., Elam, G., Kominiarek, M. A., Odoms-Young, A., Kessee, N., Hamm, A., Tussing-Humphreys, L., & Koenig, M. D. (2023). Feasibility Study of Lactobacillus Plantarum 299v Probiotic Supplementation in an Urban Academic Facility among Diverse Pregnant Individuals. Nutrients, 15(4). https://doi.org/10.3390/nu15040875
Jassim, M. A., Ayed, H. S., & Saleh, H. M. (2020). Effect of Some Fermented Milk on Blood Picture of Hypercholesterolemic Rats. International Journal of Interdisciplinary Environmental Studies, 12(13), 125–129. http://dx.doi.org/10.13140/RG.2.2.34834.40640
Kazem, Y. I., Mahmoud, M. H., Essa, H. A., Azmy, O., Kandeel, W. A., Al-Moghazy, M., El-Attar, I., Hasheesh, A., & Mehanna, N. S. (2021). Role of Bifidobacterium spp. Intake in Improving Depressive Mood and Well-Being and Its Link to Kynurenine Blood Level: An Interventional Study. Journal of Complementary & Integrative Medicine, 20(1), 223–232. https://doi.org/10.1515/jcim-2021-0351
Kurniati, I. (2020). Anemia Defisiensi Zat Besi (Fe). Jurnal Kedokteran Universitas Lampung, 4(1), 18–33. https://doi.org/10.23960/jkunila4118-33
Lailla, M., Zainar, Z., & Fitri, A. (2021). Perbandingan Hasil Pemeriksaan Hemoglobin Secara Digital terhadap Hasil Pemeriksaan Hemoglobin Secara Cyanmethemoglobin. Jurnal Pengelolaan Laboratorium Pendidikan, 3(2), 63–68. https://doi.org/10.14710/jplp.3.2.63-68
Le Port, A., Bernard, T., Hidrobo, M., Birba, O., Rawat, R., & Ruel, M. T. (2017). Delivery of Iron-Fortified Yoghurt, Through a Dairy Value Chain Program, Increases Hemoglobin Concentration Among Children 24 to 59 Months Old in Northern Senegal: A Cluster-Randomized Control Trial. PLoS One, 12(2), 1–17. https://doi.org/10.1371/journal.pone.0172198
Purnasari, P. W., Mayangsari, C. P., Yuniarifa, C. (2021). The Effects of Probiotic and Zinc on Hemoglobin Levels in Malnourished Rats. Amerta Nutr, 341–346. https://doi.org/10.20473/amnt.v5i4.2021.341-346
Rosen, G. M., Morrissette, S., Larson, A., Stading, P., Griffin, K. H., & Barnes, T. L. (2019). Use of a Probiotic to Enhance Iron Absorption in a Randomized Trial of Pediatric Patients Presenting with Iron Deficiency. The Journal of Pediatrics, 192-197. https://doi.org/10.1016/j.jpeds.2018.12.026
Shubham, K., Anukiruthika, T., Dutta, S., Kashyap, A. V., Moses, J. A., & Anandharamakrishnan, C. (2020). Iron Deficiency Anemia: A Comprehensive Review on Iron Absorption, Bioavailability and Emerging Food Fortification Approaches. Trends in Food Science and Technology, 99, 58–75. https://doi.org/10.1016/j.tifs.2020.02.021
Takaragawa, M., Sakuraba, K., & Suzuki, Y. (2022). Heat-Killed Lactococcus lactis Subsp. Cremoris H61 Altered the Iron Status of Young Women: A Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Comparative Study. Nutrients, 14(15). https://doi.org/10.3390/nu14153144
WHO. (2021). Micronutrients. https://www.who.int/health-topics/micronutrients
Yajnik, C., Kasture, S., Kantikar, V., Lubree, H., Bhat, D., Raut, D., Memane, N., Bhalerao, A., Ladkat, R., Yajnik, P., Tomar, S., Limaye, T., & Phatak, S. (2021). Efficacy of B12 Fortified Nutrient Bar and Yogurt in Improving Plasma B12 Concentrations—Results from 2 Double-Blind Randomized Placebo Controlled Trials. Food and Nutrition Bulletin, 42(4), 480–489. https://doi.org/10.1177/03795721211025448
Zakrzewska, Z., Zawartka, A., Schab, M., Martyniak, A., Skoczeń, S., Tomasik, P. J., & Wędrychowicz, A. (2022). Prebiotics, Probiotics, and Postbiotics in the Prevention and Treatment of Anemia. Microorganisms, 10(7), 1–15. https://doi.org/10.3390/microorganisms10071330
Barkhidarian, B., Roldos, L., Iskandar, M. M., Saedisomeolia, A., & Kubow, S. (2021). Probiotic Supplementation and Micronutrient Status in Healthy Subjects: A Systematic Review of Clinical Trials. Nutrients, 13(9), 1–20. https://doi.org/10.3390/nu13093001
Bintsis, T., & Papademas, P. (2022). The Evolution of Fermented Milks, from Artisanal to Industrial Products: A Critical Review. Fermentation, 8(12), 1–21. https://doi.org/10.3390/fermentation8120679
Gohel, M. K., Prajapati, J. B., Mudgal, S. V., Pandya, H. V., Singh, U. S., Trivedi, S. S., Phatak, A. G., & Patel, R. M. (2016). Effect of Probiotic Dietary Intervention on Calcium and Haematological Parameters in Geriatrics. Journal of Clinical and Diagnostic Research, 10(4), LC05–LC09. https://doi.org/10.7860/JCDR/2021/18877.7627
Gomaa, M. A. E., Allam, M. G., Haridi, A. A. I. M., Eliwa, A. E. M., & Darwish, A. M. G. (2022). High-Protein Concentrated Pro-Yogurt (Pro-WPI) Enriched with Whey Protein Isolate Improved Athletic Anemia and Performance in a Placebo-Controlled Study. Frontiers in Nutrition, 8, 1–10. https://doi.org/10.3389/fnut.2021.788446
Helmizar, H., & Surono, I. S. (2020). Characteristics of Amino Acid, Micronutrient and Probiotic Isolated from Dadih and Their Benefits for Pregnant Mothers and Outcomes in West Sumatra, Indonesia. Global Journal of Health Science, 12(1), 116-123. https://doi.org/10.5539/gjhs.v12n1p116
Helmyati, S., Rahayu, E. S., Kandarina, B. J. I ., & Juffrie, M. (2020). No Difference between Iron Supplementation Only and Iron Supplementation with Synbiotic Fermented Milk on Iron Status, Growth, and Gut Microbiota Profile in Elementary School Children with Iron Deficiency. Current Nutrition & Food Science, 16(2), 1–8. https://doi.org/10.2174/1573401314666181017110706
Hemphill, N. O., Pezley, L., Steffen, A., Elam, G., Kominiarek, M. A., Odoms-Young, A., Kessee, N., Hamm, A., Tussing-Humphreys, L., & Koenig, M. D. (2023). Feasibility Study of Lactobacillus Plantarum 299v Probiotic Supplementation in an Urban Academic Facility among Diverse Pregnant Individuals. Nutrients, 15(4). https://doi.org/10.3390/nu15040875
Jassim, M. A., Ayed, H. S., & Saleh, H. M. (2020). Effect of Some Fermented Milk on Blood Picture of Hypercholesterolemic Rats. International Journal of Interdisciplinary Environmental Studies, 12(13), 125–129. http://dx.doi.org/10.13140/RG.2.2.34834.40640
Kazem, Y. I., Mahmoud, M. H., Essa, H. A., Azmy, O., Kandeel, W. A., Al-Moghazy, M., El-Attar, I., Hasheesh, A., & Mehanna, N. S. (2021). Role of Bifidobacterium spp. Intake in Improving Depressive Mood and Well-Being and Its Link to Kynurenine Blood Level: An Interventional Study. Journal of Complementary & Integrative Medicine, 20(1), 223–232. https://doi.org/10.1515/jcim-2021-0351
Kurniati, I. (2020). Anemia Defisiensi Zat Besi (Fe). Jurnal Kedokteran Universitas Lampung, 4(1), 18–33. https://doi.org/10.23960/jkunila4118-33
Lailla, M., Zainar, Z., & Fitri, A. (2021). Perbandingan Hasil Pemeriksaan Hemoglobin Secara Digital terhadap Hasil Pemeriksaan Hemoglobin Secara Cyanmethemoglobin. Jurnal Pengelolaan Laboratorium Pendidikan, 3(2), 63–68. https://doi.org/10.14710/jplp.3.2.63-68
Le Port, A., Bernard, T., Hidrobo, M., Birba, O., Rawat, R., & Ruel, M. T. (2017). Delivery of Iron-Fortified Yoghurt, Through a Dairy Value Chain Program, Increases Hemoglobin Concentration Among Children 24 to 59 Months Old in Northern Senegal: A Cluster-Randomized Control Trial. PLoS One, 12(2), 1–17. https://doi.org/10.1371/journal.pone.0172198
Purnasari, P. W., Mayangsari, C. P., Yuniarifa, C. (2021). The Effects of Probiotic and Zinc on Hemoglobin Levels in Malnourished Rats. Amerta Nutr, 341–346. https://doi.org/10.20473/amnt.v5i4.2021.341-346
Rosen, G. M., Morrissette, S., Larson, A., Stading, P., Griffin, K. H., & Barnes, T. L. (2019). Use of a Probiotic to Enhance Iron Absorption in a Randomized Trial of Pediatric Patients Presenting with Iron Deficiency. The Journal of Pediatrics, 192-197. https://doi.org/10.1016/j.jpeds.2018.12.026
Shubham, K., Anukiruthika, T., Dutta, S., Kashyap, A. V., Moses, J. A., & Anandharamakrishnan, C. (2020). Iron Deficiency Anemia: A Comprehensive Review on Iron Absorption, Bioavailability and Emerging Food Fortification Approaches. Trends in Food Science and Technology, 99, 58–75. https://doi.org/10.1016/j.tifs.2020.02.021
Takaragawa, M., Sakuraba, K., & Suzuki, Y. (2022). Heat-Killed Lactococcus lactis Subsp. Cremoris H61 Altered the Iron Status of Young Women: A Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Comparative Study. Nutrients, 14(15). https://doi.org/10.3390/nu14153144
WHO. (2021). Micronutrients. https://www.who.int/health-topics/micronutrients
Yajnik, C., Kasture, S., Kantikar, V., Lubree, H., Bhat, D., Raut, D., Memane, N., Bhalerao, A., Ladkat, R., Yajnik, P., Tomar, S., Limaye, T., & Phatak, S. (2021). Efficacy of B12 Fortified Nutrient Bar and Yogurt in Improving Plasma B12 Concentrations—Results from 2 Double-Blind Randomized Placebo Controlled Trials. Food and Nutrition Bulletin, 42(4), 480–489. https://doi.org/10.1177/03795721211025448
Zakrzewska, Z., Zawartka, A., Schab, M., Martyniak, A., Skoczeń, S., Tomasik, P. J., & Wędrychowicz, A. (2022). Prebiotics, Probiotics, and Postbiotics in the Prevention and Treatment of Anemia. Microorganisms, 10(7), 1–15. https://doi.org/10.3390/microorganisms10071330
Published
2024-03-13
Section
Articles
Copyright (c) 2024 Annisa Furkaniaty, Gemala Anjani, Edward Kurnia Setiawan Limijadi, Anang Mohamad Legowo, Ahmad Syauqy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
