Efektivitas Virtual Reality terhadap Penurunan Nyeri Prosedural pada Anak dengan Kanker

  • Apriyani Apriyani Universitas Indonesia
  • Yati Afiyanti Universitas Indonesia
  • Tuti Nuraini Universitas Indonesia


This study aims to determine the effectiveness of Virtual Reality (VR) to reduce procedural pain in children with cancer. The method use is a systematic review by collecting articles from the Proquest, Sage Journals, ScienceDirect and PubMed databases. The results describe that children with cancer in the VR group reported lower pain scores compared to the control group, both pain scores reported by children and pain scores reported by parents. Conclusions, the use of VR is effective in reducing prosedural pain in children with cancer.

Keywords: Children With Cancer, Procedural Pain, Virtual Reality


Burrai, F., Sguanci, M., Petrucci, G., De Marinis, M. G., & Piredda, M. (2023). Effectiveness of Immersive Virtual Reality on Anxiety, Fatigue and Pain in Patients with Cancer Undergoing Chemotherapy: A Systematic Review and Meta-Analysis. European Journal of Oncology Nursing, 64(February), 102340. https://doi.org/10.1016/j.ejon.2023.102340

Çakir, S. K., & Evirgen, S. (2021). The Effect of Virtual Reality on Pain and Anxiety During Colonoscopy: A Randomized Controlled Trial. Turkish Journal of Gastroenterology, 32(5), 451–457. https://doi.org/10.5152/tjg.2021.191081

Chow, H., Hon, J., Chua, W., & Chuan, A. (2021). Effect of Virtual Reality Therapy in Reducing Pain and Anxiety for Cancer-Related Medical Procedures: A Systematic Narrative Review. Journal of Pain and Symptom Management, 61(2), 384–394. https://doi.org/10.1016/j.jpainsymman.2020.08.016

Comparcini, D., Simonetti, V., Galli, F., Saltarella, I., Altamura, C., Tomietto, M., Desaphy, J. F., & Cicolini, G. (2023). Immersive and Non-Immersive Virtual Reality for Pain and Anxiety Management in Pediatric Patients with Hematological or Solid Cancer: A Systematic Review. Cancers, 15(3). https://doi.org/10.3390/cancers15030985

Czech, O., Wrzeciono, A., Batalík, L., Szczepańska-Gieracha, J., Malicka, I., & Rutkowski, S. (2022). Virtual Reality Intervention as a Support Method during Wound Care and Rehabilitation after Burns: A Systematic Review and Meta-analysis. Complementary Therapies in Medicine, 68(April). https://doi.org/10.1016/j.ctim.2022.102837

Erdős, S., & Horváth, K. (2023). The Impact of Virtual Reality (VR) on Psychological and Physiological Variables in Children Receiving Chemotherapy: A Pilot Cross-Over Study. Integrative Cancer Therapies, 22. https://doi.org/10.1177/15347354231168984

Gerçeker, G. Ö., Bektaş, M., Aydınok, Y., Ören, H., Ellidokuz, H., & Olgun, N. (2021). The Effect of Virtual Reality on Pain, Fear, and Anxiety During Access of A Port with Huber Needle in Pediatric Hematology-Oncology Patients: Randomized Controlled Trial. European Journal of Oncology Nursing, 50(December 2020), 1–7. https://doi.org/10.1016/j.ejon.2020.101886

Hoag, J. A., Karst, J., Bingen, K., Palou-Torres, A., & Yan, K. (2022). Distracting Through Procedural Pain and Distress Using Virtual Reality and Guided Imagery in Pediatric, Adolescent, and Young Adult Patients: Randomized Controlled Trial. Journal of Medical Internet Research, 24(4). https://doi.org/10.2196/30260

Hundert, A. S., Birnie, K. A., Abla, O., Positano, K., Cassiani, C., Lloyd, S., Tiessen, P. H., Lalloo, C., Jibb, L. A., & Stinson, J. (2022). A Pilot Randomized Controlled Trial of Virtual Reality Distraction to Reduce Procedural Pain during Subcutaneous Port Access in Children and Adolescents with Cancer. Clinical Journal of Pain, 38(3), 189–196. https://doi.org/10.1097/AJP.0000000000001017

Ibrahim, F. E., Elsayed, N. N. A. M., & Zayed, H. H. (2021). A Survey on the Effectiveness of Virtual Reality-based Therapy and Pain Management. International Journal of Advanced Computer Science and Applications, 12(7), 602–616. https://doi.org/10.14569/IJACSA.2021.0120769

Ioannou, A., Papastavrou, E., Avraamides, M. N., & Charalambous, A. (2020). Virtual Reality and Symptoms Management of Anxiety, Depression, Fatigue, and Pain: A Systematic Review. SAGE Open Nursing, 6. https://doi.org/10.1177/2377960820936163

Lier, E. J., de Vries, M., Steggink, E. M., Ten Broek, R. P., & van Goor, H. (2023). Effect Modifiers of Virtual Reality in Pain Management: A Systematic Review and Meta-Regression Analysis. Pain, 164(8), 1658-1665. https://doi.org/ 10.1097/j.pain.0000000000002883

Loeffen, E. A. H., Mulder, R. L., Font-Gonzalez, A., Leroy, P. L. J. M., Dick, B. D., Taddio, A., Ljungman, G., Jibb, L. A., Tutelman, P. R., Liossi, C., Twycross, A., Positano, K., Knops, R. R., Wijnen, M., van de Wetering, M. D., Kremer, L. C. M., Dupuis, L. L., Campbell, F., & Tissing, W. J. E. (2020). Reducing Pain and Distress Related to Needle Procedures in Children with Cancer: A Clinical Practice Guideline. European Journal of Cancer, 131, 53–67. https://doi.org/10.1016/j.ejca.2020.02.039

Menekli, T., Yaprak, B., & Doğan, R. (2022). The Effect of Virtual Reality Distraction Intervention on Pain, Anxiety, and Vital Signs of Oncology Patients Undergoing Port Catheter Implantation: A Randomized Controlled Study. Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses, 23(5), 585–590. https://doi.org/10.1016/j.pmn.2022.03.004

Rygh, L., Johal, S., Johnson, H., & Karlson, C. W. (2023). Virtual Reality for Pediatric Oncology Port-A-Cath Access: A Pilot Effectiveness Study. Journal of Pediatric Hematology/Oncology Nursing. https://doi.org/10.1177/27527530221147875

Semerci, R., Akgün Kostak, M., Eren, T., & Avci, G. (2021). Effects of Virtual Reality on Pain During Venous Port Access in Pediatric Oncology Patients: A Randomized Controlled Study. Journal of Pediatric Oncology Nursing, 38(2), 142–151. https://doi.org/10.1177/1043454220975702

Tennant, M., Youssef, G. J., McGillivray, J., Clark, T. J., McMillan, L., & McCarthy, M. C. (2020). Exploring the use of Immersive Virtual Reality to Enhance Psychological Well-Being in Pediatric Oncology: A pilot randomized controlled trial. European Journal of Oncology Nursing, 48(July 2020), 101804. https://doi.org/10.1016/j.ejon.2020.101804

Tsegaye, D., Yazew, A., Gedfew, M., Yilak, G., & Yalew, Z. M. (2023). Non-Pharmacological Pain Management Practice and Associated Factors Among Nurses Working at Comprehensive Specialized Hospitals. SAGE Open Nursing, 9. https://doi.org/10.1177/23779608231158979

Wong, C. L., Li, C. K., Chan, C. W. H., Choi, K. C., Chen, J., Yeung, M. T., & Chan, O. N. (2021). Virtual Reality Intervention Targeting Pain and Anxiety Among Pediatric Cancer Patients Undergoing Peripheral Intravenous Cannulation: A Randomized Controlled Trial. Cancer Nursing, 44(6). https://journals.lww.com/cancernursingonline/Fulltext/2021/11000/Virtual_Reality_Intervention_Targeting_Pain_and.3.aspx

Zeleke, S., Kassaw, A., & Eshetie, Y. (2021). Non-Pharmacological Pain Management Practice and Barriers among Nurses Working in Debre Tabor Comprehensive Specialized Hospital, Ethiopia. PLoS ONE, 16(6 June), 1–11. https://doi.org/10.1371/journal.pone.0253086
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