Intervensi Non Farmakologis untuk Memperbaiki Status Fungsional Pasien Kanker dengan Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Abstract
This study aims to identify non-pharmacological interventions that can improve the functional status of cancer patients with chemotherapy-induced peripheral neuropathy (CIPN). The research method uses a systematic review through literature searches from 4 databases: SAGE, PUBMED, SCIENCE DIRECT, and PROQUEST. The research results show that from 12 research articles, non-pharmacological interventions to improve functional status in CIPN can be grouped into physical and non-physical interventions. Physical interventions include physical exercise and stimulation, while non-physical interventions are through self-management. In conclusion, physical intervention effectively reduces the pain scale and sensory symptoms of CIPN, which improves the patient's functional status and quality of life. However, in some literature, it is stated that a combination with pharmacological therapy can reduce CIPN complaints.
Keywords: CIPN, Non-Pharmacological Intervention, Functional Status
References
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Smith, T. J., Razzak, A. R., Blackford, A. L., Ensminger, J., Saiki, C., Longo-Schoberlein, D., & Loprinzi, C. L. (2020). A Pilot Randomized Sham-Controlled Trial of MC5-A Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy (CIPN). Journal of Palliative Care, 35(1), 53–58. https://doi.org/10.1177/0825859719827589
Srivastava, S. P., Sinha, A. P., Sharma, K. K., & Malik, P. S. (2022a). Severity, Risk Factors and Quality of Life of Patients associated with Chemotherapy-Induced Peripheral Neuropathy. Clinical Nursing Research, 31(6), 1080–1090. https://doi.org/10.1177/10547738221085613
Tanay, M. A. L., Armes, J., Moss-Morris, R., Rafferty, A. M., & Robert, G. (2023). A Systematic Review of Behavioural And Exercise Interventions for The Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy Symptoms. Journal of Cancer Survivorship, 17(1), 254–277. https://doi.org/10.1007/s11764-021-00997-w
Wang, M., Pei, Z., & Molassiotis, A. (2022). Recent Advances in Managing Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review. European Journal of Oncology Nursing, 58. https://doi.org/10.1016/j.ejon.2022.102134
Yeh, C. H., Caswell, K., Pandiri, S., Sair, H., Lukkahatai, N., Campbell, C. M., Stearns, V., Van de Castle, B., Perrin, N., Smith, T. J., & Saligan, L. N. (2020). Dynamic Brain Activity Following Auricular Point Acupressure in Chemotherapy-Induced Neuropathy: A Pilot Longitudinal Functional Magnetic Resonance Imaging Study. Global Advances In Health and Medicine, 9. https://doi.org/10.1177/2164956120906092
Chan, K., Lui, L., Lam, Y., Yu, K., Lau, K., Lai, M., Lau, W., Tai, L., Mak, C., Bian, Z., & Zhong, L. L. D. (2023). Efficacy and Safety of Electroacupuncture for Oxaliplatin-Induced Peripheral Neuropathy in Colorectal Cancer Patients: A Single-Blinded, Randomized, Sham-Controlled Trial. Acupuncture in Medicine, 41(5), 268–283. https://doi.org/10.1177/09645284221125421
Chen, S. C., Huang, H. P., Huang, W. S., Lin, Y. C., Chu, T. P., Beaton, R. D., & Jane, S. W. (2020). Non-Randomized Preliminary Study of An Education and Elastic-Band Resistance Exercise Program on Severity of Neuropathy, Physical Function, Muscle Strength and Endurance & Quality of Life in Colorectal Cancer Patients Experiencing Oxaliplatin-Induced Peripheral Neuropathy. European Journal of Oncology Nursing, 49, 101834. https://doi.org/10.1016/j.ejon.2020.101834
Galantino, M. L., Tiger, R., Brooks, J., Jang, S., & Wilson, K. (2019). Impact of Somatic Yoga and Meditation on Fall Risk, Function, and Quality of Life for Chemotherapy-Induced Peripheral Neuropathy Syndrome in Cancer Survivors. Integrative Cancer Therapies, 18, 1534735419850627. https://doi.org/10.1177/1534735419850627
Greenlee, H., Crew, K. D., Capodice, J., Awad, D., Buono, D., Shi, Z., Jeffres, A., Wyse, S., Whitman, W., Trivedi, M. S., Kalinsky, K., & Hershman, D. L. (2016). Randomized Sham-Controlled Pilot Trial of Weekly Electro-Acupuncture for The Prevention of Taxane-Induced Peripheral Neuropathy in Women with Early Stage Breast Cancer. Breast Cancer Research and Treatment, 156(3), 453–464. https://doi.org/10.1007/s10549-016-3759-2
Ikio, Y., Sagari, A., Nakashima, A., Matsuda, D., Sawai, T., & Higashi, T. (2022). Efficacy of Combined Hand Exercise Intervention in Patients with Chemotherapy-Induced Peripheral Neuropathy: A Pilot Randomized Controlled Trial. Supportive Care in Cancer, 30(6), 4981–4992. https://doi.org/10.1007/s00520-022-06846-5
Izgu, N., Metin, Z. G., Karadas, C., Ozdemir, L., Çetin, N., & Demirci, U. (2019). Prevention of Chemotherapy-Induced Peripheral Neuropathy with Classical Massage in Breast Cancer Patients Receiving Paclitaxel: An Assessor-Blinded Randomized Controlled Trial. European Journal of Oncology Nursing, 40, 36–43. https://doi.org/10.1016/j.ejon.2019.03.002
Kanda, K., Ishida, K., Kyota, A., Ishihara, C., Fujimoto, K., Hosokawa, M., & Mochizuki, R. (2023). Randomized Clinical Trial Quantifying The Effectiveness of A Self-Monitoring Intervention in Cancer Patients with Peripheral Neuropathy: A Quantitative Study. Asia-Pacific Journal of Oncology Nursing, 10(4), 100198. https://doi.org/10.1016/j.apjon.2023.100198
Kneis, S., Wehrle, A., Müller, J., Maurer, C., Ihorst, G., Gollhofer, A., & Bertz, H. (2019). It’s Never Too Late - Balance And Endurance Training Improves Functional Performance, Quality of Life, and Alleviates Neuropathic Symptoms in Cancer Survivors Suffering from Chemotherapy-Induced Peripheral Neuropathy: Results of A Randomized Controlled Trial. BMC Cancer, 19(1). https://doi.org/10.1186/s12885-019-5522-7
Komatsu, H., Yagasaki, K., Komatsu, Y., Yamauchi, H., Yamauchi, T., Shimokawa, T., & Doorenbos, A. (2019). Falls and Functional Impairments in Breast Cancer Patients with Chemotherapy-Induced Peripheral Neuropathy. Asia-Pacific Journal of Oncology Nursing, 6(3), 253–260. https://doi.org/10.4103/apjon.apjon_7_19
Langley-Brady, D. L., Campbell, R. T., Maihle, N. J., Barnes, V. A., Bratton, A. R., & Zadinsky, J. K. (2023). A Pilot Randomized Controlled Trial Evaluating Essential Oils for Chemotherapy-Induced Peripheral Neuropathy. Pain Management Nursing, 24(3), 289–298. https://doi.org/10.1016/j.pmn.2022.12.008
Lu, W., Giobbie-Hurder, A., Freedman, R. A., Shin, I. H., Lin, N. U., Partridge, A. H., Rosenthal, D. S., & Ligibel, J. A. (2020). Acupuncture for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Survivors: A Randomized Controlled Pilot Trial. The Oncologist, 25(4), 310–318. https://doi.org/10.1634/theoncologist.2019-0489
Monfort, S. M., Pan, X., Loprinzi, C. L., Lustberg, M. B., & Chaudhari, A. M. W. (2019). Impaired Postural Control and Altered Sensory Organization During Quiet Stance Following Neurotoxic Chemotherapy: A Preliminary Study. Integrative Cancer Therapies, 18. https://doi.org/10.1177/1534735419828823
Saraboon, C., & Siriphorn, A. (2021). Effects of Foam Pad Balance Exercises on Cancer Patients Undergoing Chemotherapy: A Randomized Control Trial. Journal of Bodywork and Movement Therapies, 28, 164–171. https://doi.org/10.1016/j.jbmt.2021.07.013
Shim, H. S., Bae, C., Wang, J., Lee, K. H., Hankerd, K. M., Kim, H. K., Chung, J. M., & La, J. H. (2019). Peripheral and Central Oxidative Stress in Chemotherapy-Induced Neuropathic Pain. Molecular Pain, 15. https://doi.org/10.1177/1744806919840098
Smith, T. J., Razzak, A. R., Blackford, A. L., Ensminger, J., Saiki, C., Longo-Schoberlein, D., & Loprinzi, C. L. (2020). A Pilot Randomized Sham-Controlled Trial of MC5-A Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy (CIPN). Journal of Palliative Care, 35(1), 53–58. https://doi.org/10.1177/0825859719827589
Srivastava, S. P., Sinha, A. P., Sharma, K. K., & Malik, P. S. (2022a). Severity, Risk Factors and Quality of Life of Patients associated with Chemotherapy-Induced Peripheral Neuropathy. Clinical Nursing Research, 31(6), 1080–1090. https://doi.org/10.1177/10547738221085613
Tanay, M. A. L., Armes, J., Moss-Morris, R., Rafferty, A. M., & Robert, G. (2023). A Systematic Review of Behavioural And Exercise Interventions for The Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy Symptoms. Journal of Cancer Survivorship, 17(1), 254–277. https://doi.org/10.1007/s11764-021-00997-w
Wang, M., Pei, Z., & Molassiotis, A. (2022). Recent Advances in Managing Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review. European Journal of Oncology Nursing, 58. https://doi.org/10.1016/j.ejon.2022.102134
Yeh, C. H., Caswell, K., Pandiri, S., Sair, H., Lukkahatai, N., Campbell, C. M., Stearns, V., Van de Castle, B., Perrin, N., Smith, T. J., & Saligan, L. N. (2020). Dynamic Brain Activity Following Auricular Point Acupressure in Chemotherapy-Induced Neuropathy: A Pilot Longitudinal Functional Magnetic Resonance Imaging Study. Global Advances In Health and Medicine, 9. https://doi.org/10.1177/2164956120906092
Published
2024-05-25
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Copyright (c) 2024 Hani Handriani, Yati Afiyati, Allenidekania Allenidekania
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