Perbandingan Skin Preparation Kombinasi Alkohol 70% dan Chlorhexidine Gluconate 4 % dengan Kombinasi Chlorhexidine Gluconate 4% dan Povidone Iodine 10% terhadap Jumlah Koloni Kuman pada Persiapan Pembedahan
Abstract
This study aims to examine differences in the number of bacterial colonies after skin preparation using a combination of 70% alcohol and 4% chlorhexidine gluconate with 4% chlorhexidine gluconate and 10% povidone-iodine. This study used a quasi-experimental method with a pre-post test design. The results showed a decrease in the number of bacterial colonies by 99.84% in the 70% alcohol group and 4% chlorhexidine gluconate, and 99.77% in the 4% chlorhexidine gluconate and 10% povidone-iodine groups. While the difference in the number of bacterial colonies between the two groups, there was no significant difference with a p-value of 0.320 > 0.05. In conclusion, both groups effectively reduced germ numbers, but there was no significant difference in effectiveness between the two groups.
Keywords: Alcohol, Chlorhexidine, Iodine, Skin Preparation
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Atnawanty, T., Yona, S., & Maria, R. (2020). Efektifitas Mandi Chlorhexidine Gluconate Terhadap Penurunan Angka Kejadian Hais: Literature Review. Jurnal Riset Kesehatan Nasional, 4(2), 1–7. https://ejournal.itekes-bali.ac.id/jrkn/article/view/234
Bangun, P., Hanafie, A., & Wijaya, D. W. (2016). Perbandingan Chlorhexidine 2%-Alkohol 70% dengan Povidone Iodine 10%-Alkohol 70% terhadap Penurunan Kepadatan Kuman dalam Mengurangi CRBSI Pada Pemasangan CVC. JAI (Jurnal Anestesiologi Indonesia), 8(2), 93–104. https://doi.org/10.14710/jai.v8i2.19808
Challacombe, S. J., Kirk-Bayley, J., Sunkaraneni, V. S., & Combes, J. (2020). Povidone Iodine. British Dental Journal, 228(9), 656–657. https://doi.org/10.1038/s41415-020-1589-4
Guenezan, J., Marjanovic, N., Drugeon, B., Neill, R. O., Liuu, E., Roblot, F., Palazzo, P., Bironneau, V., Prevost, F., & Paul, J. (2021). Chlorhexidine Plus Alcohol Versus Povidone Iodine Plus Alcohol, Combined or not with Innovative Devices, for Prevention of Short-Term Peripheral Venous Catheter Infection and Failure (CLEAN 3 Study): An Investigator-Initiated, Open-Label, Single Centre, Randomised-Controlled, Two-by-Two Factorial Trial. The Lancet Infectious Diseases, 21(7), 1038–1048. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30738-6/fulltext
Heriyati, H., & Astuti, A. (2020). Hubungan Pencegahan dan Pengendalian Infeksi Nosokomial di Rumah Sakit. Jurnal Pendidikan Kesehatan, 9(1), 87–92. https://ojs.poltekkes-malang.ac.id/index.php/jpk/article/download/1465/237
Kusuma, Y., Pinatih, K. J. P., & Hendrayana, M. A. (2019). Efek Sinergis Kombinasi Chlorhexidine dan Alkohol terhadap Daya Hambat Pertumbuhan Staphylococcus Aureus. E-Jurnal Medika, 8(3), 139–146. https://ojs.unud.ac.id/index.php/eum/article/view/48937
Kusumaningrum, A., Sitohang, G., Satari, H. I., & Loho, T. (2018). Perbandingan Efektivitas Klorheksidin 2% dalam Isopropil Alkohol 70% dengan Antiseptik Sesuai Prosedur Operasional Standar pada Persiapan Pembedahan. Majalah Kedokteran UKI, 34(4), 160–164. http://ejournal.uki.ac.id/index.php/mk/article/view/1861
National Center for Biotechnology Information (NCBI). (2022). PubChem Compound Summary for CID 3776, Isopropyl alcohol. Pubchem.ncbi.nlm.nih.gov/compound/isopropanol.
National Center for Biotechnology Information (NCBI). (2022). PubChem Compound Summary for CID 131751496, Povidone. Pubchem.ncbi.nlm.nih.gov/compound/Povidone.
Pradiptya, Y., Haniastuti, T., & Hendrawati, H. (2021). Penggunaan Obat Kumur yang Mengandung Alkohol dan Non-Alkohol untuk Pencegahan Infeksi Silang pada Tindakan Perawatan Gigi. Jurnal Online Perpustakaan Gajah Mada. http://etd.repository.ugm.ac.id/penelitian/detail/199930
Rahman, S. (2019). Efektivitas Mandi Chlorhexidine Sebelum Operasi Elektif Ortopedi dalam Mencegah Infeksi Daerah Operasi di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh. Jurnal Kedokteran Syiah Kuala, 19(1), 41-44. https://doi.org/10.24815/jks.v19i1.10524
Riyanto, S., Ibrahim, K., & Rahayu, U. (2022). Usage of Chlorhexidine Gluconate in Skin Preparation Protocols for Surgical Preparation to Reduce the Rate of Surgical Site Infection: A Literature Review. Malaysian Journal of Medicine and Health Sciences, 18(3), 272-277. https://medic.upm.edu.my/upload/dokumen/2022022317471749_0992.pdf
Setyani, I. A. (2018). Total Bakteri pada Telapak Tangan Sebelum dan Sesudah Menggunakan Cairan Antiseptik. Universitas Muhammadiyah Semarang. http://repository.unimus.ac.id/id/eprint/1890
Published
2022-09-30
Section
Articles
Copyright (c) 2022 Slamet Riyanto, Kusman Ibrahim, Urip Rahayu
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
