Jus Wheatgrass (Rumput Gandum) untuk Mengurangi Efek Kemoterapi
Abstract
This study aims to describe and analyze the benefits of wheatgrass in reducing the effects of chemotherapy. The design of this research is a systematic narrative review. Six scientific databases were used to obtain relevant sources dealing with specific issues related to wheatgrass in reducing the effects of chemotherapy, namely Pubmed, Ebsco, Sage Journals, Clinical Key, Scopus, and Pro-quest. The study results found 655 articles, and six articles were relevant and qualified. The use of wheatgrass juice turned out to have a significant effect on treating cancer patients in reducing the impact of chemotherapy and providing alternative options for reducing the effects of chemotherapy. In conclusion, wheatgrass can increase hemoglobin and platelet levels, contain antineoplastic compounds, suppress EMT in hypoxia, and can improve the performance of P53 cells in performing apoptosis.
Keywords: Cancer, Chemotherapy, Wheatgrass
References
Avisar, A., Cohen, M., Katz, R., Kutiel, T. S., Aharon, A., & Bar-Sela, G. (2020). Wheatgrass Juice Administration and Immune Measures During Adjuvant Chemotherapy in Colon Cancer Patients: Preliminary Results. Pharmaceuticals, 13(6), 1–15. https://doi.org/10.3390/ph13060129
Bradley, S. H., Kennedy, M. P. T., & Neal, R. D. (2019). Recognising Lung Cancer in Primary Care. Advances in Therapy, 36(1), 19–30. https://doi.org/10.1007/s12325-018-0843-5
Chui, P. L. (2019). Cancer-and Chemotherapy-Related Symptoms and the Use of Complementary and Alternative Medicine. Asia-Pacific Journal of Oncology Nursing, 6(1), 4–6. https://doi.org/10.4103/apjon.apjon-51-18
Do, N. Y., Shin, H. J., & Lee, J. E. (2018). Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells. Nutrition Research and Practice, 11(2), 83–89. https://doi.org/10.4162/nrp.2017.11.2.83
Globocan. (2020). The Global Cancer Observatory. https://gco.iarc.fr/today/data/factsheets/populations/360-indonesia-fact-sheets.pdf
Gore, R. D., Palaskar, S. J., & Bartake, A. R. (2018). Wheatgrass: Green Blood Can Help to Fight Cancer. Journal of Clinical and Diagnostic Research, 11(6), ZC40–ZC42. https://doi.org/10.7860/JCDR/2017/26316.10057
Hayati, R. N., & Yuniarti, E. (2020). The Difference Chlorophyll of Wheat Grass (Triticum aestivum L.) Planted with Different Media. Serambi Biologi, 5(1), 25–28. http://ejournal.unp.ac.id/students/index.php/bio/article/view/5798
Oh, C. M., Lee, D., Kong, H. J., Lee, S., Won, Y. J., Jung, K. W., & Cho, H. (2020). Causes of Death among Cancer Patients in the Era of Cancer Survivorship in Korea: Attention to the Suicide and Cardiovascular Mortality. Cancer Medicine, 9(5), 1741–1752. https://doi.org/10.1002/cam4.2813
Pinsolle, J., Terzi, N., Ferrer, L., Giaj Levra, M., Toffart, A. C., & Moro-Sibilot, D. (2019). Advances in the Management of Lung Cancers. Medecine Intensive Reanimation, 28(4), 290–299. https://doi.org/10.3166/rea-2019-0091
Rajagopalan, R., Shakya, G., & Balasubramanian, S. (2018). Methanol Extract of Wheatgrass Induces G1 Cell Cycle Arrest in a p53-Dependent Manner and Down Regulates the Expression of Cyclin D1 in Human Laryngeal Cancer Cells-An in Vitro and in Silico Approach. Pharmacognosy Magazine, 11(42), 139. https://doi.org/10.4103/0973-1296.157715
Save, S., Chancier, H., Patil, M., Singh, S., Satti, N. K., Chaturbhuj, G., & Clement, B. (2019). In-Vitro Anti-Cancer and in-Vivo Immunomodulatory Activity of Two New Compounds Isolated from Wheatgrass (Triticum Aestivum L). Indian Journal of Natural Products and Resources, 10(1), 9–22. http://nopr.niscair.res.in/handle/123456789/50430
Viale, P. (2020). The American Cancer Society’s Facts & Figures: 2020 Edition. Journal of the Advanced Practitioner in Oncology, 11(2), 135–136. https://doi.org/10.6004/jadpro.2020.11.2.1
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