Pemanfaatan Pliek U (Bumbu Khas Aceh) sebagai Krim Antibakteri
Abstract
This study aims to determine the antibacterial activity of Pliek U ethanol extract cream against Staphylococcus aureus. The method was an experimental method with a completely randomized design (CRD) on five treatments, namely positive control, negative control, F1, F2, and F3, each with four repetitions. Antibacterial testing was carried out using the disc diffusion method. The results showed that the average diameters of F1, F2 and F3 were 12.65 mm, 14.9 mm and 12.92 mm, which were included in the solid antibacterial category in inhibiting the activity of Staphylococcus aureus bacteria. Pliek U can be formulated as a cream preparation, meets the requirements for quality tests for cream preparations and has met SNI standard parameters. In conclusion, Pliek U ethanol extract cream has antibacterial activity with the most optimum effectiveness at a concentration of 5%.
Keywords: Antibacterial, Cream, Pliek U, Staphylococcus aureus
References
Mailana, D., Nuryanti, N., & Harwoko, H. (2016). Formulasi Sediaan Krim Antioksidan Ekstrak Etanolik Daun Alpukat (Persea americana Mill.). Acta Pharmaciae Indonesia, 4(2), 7–15. http://jos.unsoed.ac.id/index.php/api/article/view/1468/993
Majid, N. S., Yamlean, P. V. Y., & Citraningtyas, G. (2019). Formulasi dan Uji Efektivitas Krim Antibakteri Ekstrak Daun Nangka (Artocarpus heterophyllus Lam.) terhadap Bakteri Staphylococcus aureus. Pharmacon, 8(1), 225–233. https://doi.org/10.35799/pha.8.2019.29257
Novita, R., Munira, M., & Hayati, R. (2017). Formulasi Sediaan Salep Ekstrak Etanol Pliek U sebagai Antibakteri. AcTion: Aceh Nutrition Journal, 2(2), 103–108. http://dx.doi.org/10.30867/action.v2i2.62
Primayuda, Y. (2016). Uji Aktivitas Antibakteri Krim Ekstrak Etanol Kulit Batang Kesambi (Schleichera oleosa MERR) terhadap Staphylococcus aureus ATCC 25923 Secara In Vivo. Skripsi. Universitas Setia Budi Surakarta
Putri, E., & Amilda, P. (2019). Perbedaan Potensi Bakteriostatik Ekstrak Daun Jelatong (Dendrocnide sinuata) terhadap Bakteri Staphylococcus aureus dan Salmonella typhi Secara In Vitro. Variasi : Majalah Ilmiah Universitas Almuslim, 11(6), 19–23. http://jurnal.umuslim.ac.id/index.php/VRS/article/download/1597/1903
Rinaldi, R., Samingan, S., & Iswadi, I. (2016). Isolasi dan Identifikasi Jamur pada Proses Pembuatan Pliek U. Prosiding Seminar Nasional Biotik, 4(1), 273-279. http://dx.doi.org/10.22373/pbio.v4i1.2580
Sambou, C. N. (2017). Pengembangan Produk Sediaan Gel Kombinasi Ekstrak Daun Sirsak (Annona muricita L.) dengan Ekstrak Rimpang Temulawak (Curcuma xanthorhiza Roxb.) sebagai Antibakteri Penyebab Jerawat (Propionibac terium acne dan Staphylococcus epidermidis). Jurnal Pharmacon, 2(2), 4–6. https://doi.org/10.35799/pha.6.2017.17973
Sulastri, E., Mappiratu, M., & Sari, A. K. (2016). Uji Aktivitas Antibakteri Krim Asam Laurat terhadap Staphylococcus aureus ATCC 25923 dan Pseudomonas aeruginosa ATCC 27853. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 2(2), 59–67. https://doi.org/10.22487/j24428744.2016.v2.i2.5955
